2025

Targeting the MAPK signaling pathway: implications and prospects of flavonoids in 3P medicine as modulators of cancer cell plasticity and therapeutic resistance in breast cancer patients.

Kubatka P, Bojkova B, Nosalova N, Huniadi M, Samuel SM, Sreenesh B, Hrklova G, Kajo K, Hornak S, Cizkova D, Bubnov R, Smokovski I, Büsselberg D, Golubnitschaja O. EPMA J. 2025;16(2):437-463. doi: 10.1007/s13167-025-00407-6. https://pubmed.ncbi.nlm.nih.gov/40438489/

Mitochondrial medicine: "from bench to bedside" 3PM-guided concept.

Shao Q, Ndzie Noah ML, Golubnitschaja O, Zhan X. EPMA J. 2025;16(2):239-264. doi: 10.1007/s13167-025-00409-4. https://pubmed.ncbi.nlm.nih.gov/40438494/

Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications.

Pushpanathan K, Bai Y, Lei X, Goh JHL, Xue CC, Yew SME, Chee M, Quek TC, Peng Q, Soh ZD, Yu MCY, Zhou J, Wang Y, Jonas JB, Wang X, Sim X, Tai ES, Sabanayagam C, Goh RSM, Liu Y, Cheng CY, Tham YC. EPMA J. 2025;16(2):519-533. doi: 10.1007/s13167-025-00412-9. https://pubmed.ncbi.nlm.nih.gov/40438493/

Systemic inflammation at the oral-ocular interface: a 3P medicine perspective on the relationship between periodontitis and eye diseases.

Oh E, Jun JH, Choi JY, Yoo TK. EPMA J. 2025;16(3):571-587. doi: 10.1007/s13167-025-00415-6. https://pubmed.ncbi.nlm.nih.gov/40948984/

Creatine as a mitochondrial theranostic in predictive, preventive, and personalized medicine.

Ostojic SM, Rátgéber L. EPMA J. 2025;16(3):541-553. doi: 10.1007/s13167-025-00420-9. https://pubmed.ncbi.nlm.nih.gov/40948982/

2026

Transforming telemedicine through predictive, preventive, and personalized medicine (PPPM): innovations, challenges, and future directions.

Yang Y, Zhang W, Liu C, Zhang H, Shen X, Liao Y, Shi W, Gui L. EPMA J. 2026;17(1):21-42. doi: 10.1007/s13167-026-00441-y. https://pubmed.ncbi.nlm.nih.gov/41822025/

Monitoring airline pilot mental health: a 3PM framework utilising digital phenotyping and AI. Emanuele E, Minoretti P. EPMA J. 2026;17(2):233-248. doi: 10.1007/s13167-026-00454-7. https://pubmed.ncbi.nlm.nih.gov/42179459/

Innovative mitochondria-based holistic 3PM approach to female health status: Facts and outlook. Pesta M, Goncharenko V, Kulda V, Polivka J, Rizaev J, Golubnitschaja O. EPMA J. 2026;17(1):1-19. doi: 10.1007/s13167-026-00438-7. https://pubmed.ncbi.nlm.nih.gov/41822023/

Vision restoration in glaucoma: improved subjective visual function after personalised digital lifestyle coaching.

El Matine JL, Lux A, Fricke L, Tahamtan M, El Matine RS, Sabel BA. EPMA J. 2026;17(2):339-350. doi: 10.1007/s13167-026-00446-7. https://pubmed.ncbi.nlm.nih.gov/42179464/

From sympathetic overdrive phenotype to malignant transformation: 3PM-guided protection against health-to-disease transition and disease progression improving individual outcomes in primary and secondary care.

Kubatka P, Kapinova A, Bojkova B, Joseph V, Hornak S, Kajo K, Büsselberg D, Smejkal K, Goncharenko V, Mrazova B, Fövényes M, Bubnov R, Kuhn W, Conde-Aranda J, Smokovski I, Stetkarova I, Golubnitschaja O. EPMA J. 2026;17(2):205-232. doi: 10.1007/s13167-026-00447-6. https://pubmed.ncbi.nlm.nih.gov/42179461/